The Setun (Russian: Сетунь) is a river in the west of Moscow and the largest tributary of the Moskva River in Moscow. The length of the river is 38 kilometers (24 mi), 20 kilometers (12 mi) of which is in Moscow itself. Its basin has an area of 190 square kilometers (73 sq mi). The Setun River originates in the village of Salariyevo in Moscow Oblast and flows into the Moskva River near Krasnoluzhsky Road Bridge, opposite of the village of Luzhniki. The river teems with roach, European perch, crucian carp, pike, and other fish, but is of no value to the fishing industry due to pollution with toxic waste.
The border territory upon the both banks is included in Setun's river valley Wildlife Sanctuary, placed in the Moscow city bounds.